Famous 40 CFR 180 Abamectin A Comprehensive Guide Abamectin, a widely used insecticide and acaricide, is regulated under the provisions of the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) by the United States Environmental Protection Agency (EPA). Specifically, it is listed as a restricted-use pesticide (RUP) and is subject to strict regulations outlined in 40 CFR 180, which sets forth the conditions and restrictions for its use. The registration of abamectin in the United States was based on its efficacy against a wide range of pests, including nematodes, insects, and mites, as well as its low toxicity to mammals and birds. It acts by disrupting the nervous system of the target organism, leading to paralysis and death. One of the key provisions of 40 CFR 180 is the requirement for reregistration of all RUPs every 15 years. This process involves a thorough review of the pesticide's safety and effectiveness, as well as its potential impacts on human health and the environment. The reevaluation of abamectin in 2007 resulted in the establishment of new maximum residue limits (MRLs) for certain crops and commodities, as well as revised label instructions for its use. In addition to the reregistration requirements, 40 CFR 180 also establishes guidelines for the handling and storage of abamectin, as well as restrictions on its use in certain areas and situations In addition to the reregistration requirements, 40 CFR 180 also establishes guidelines for the handling and storage of abamectin, as well as restrictions on its use in certain areas and situations In addition to the reregistration requirements, 40 CFR 180 also establishes guidelines for the handling and storage of abamectin, as well as restrictions on its use in certain areas and situations In addition to the reregistration requirements, 40 CFR 180 also establishes guidelines for the handling and storage of abamectin, as well as restrictions on its use in certain areas and situationsfamous 40 cfr 180 abamectin. For example, it is prohibited from being applied to food crops intended for human consumption without prior approval from the EPA. Abamectin has been the subject of several studies and evaluations over the years, and its safety and effectiveness have generally been confirmed. However, like all pesticides, it does carry certain risks and precautions must be taken when using it. This includes wearing appropriate personal protective equipment (PPE), following label instructions carefully, and avoiding contact with the product whenever possible. Overall, the regulation of abamectin under 40 CFR 180 reflects the EPA's commitment to ensuring the safe and responsible use of pesticides while protecting public health and the environment. By strictly regulating the use of this important pest control tool, the agency helps to minimize the potential risks associated with its application while still allowing for its effective use in controlling a wide range of pests.