Understanding herbicides involves recognizing the significance of managing weeds. Throughout agricultural history, weed control has been essential, predating the invention of herbicides. While cultivating crops, undesirable plants, or weeds, often emerge. These unwelcome plants can harm desired crop growth and yield by competing for resources such as water, nutrients, sunlight, and by harbouring insects and fungi.

The avermectins are derived from a family of macrocyclic lactones produced by the soil microorganism Streptomyces avermitilis. Abamectin (avermectin B1) was introduced in 1985 as a crop insecticide against mites and some insect species. The semisynthetic derivative ivermectin (22,23-dihydroavermectin B1) was introduced commercially in 1981 as an anthelmintic. T

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