Weeds are the bane of a gardener's existence. They grow, seemingly overnight, choking out healthy flowers and vegetables and starving them of water, sunlight, and nutrients. There are several weed killer methods to deal with unwanted plants.

The avermectins are derived from a family of macrocyclic lactones produced by the soil microorganism Streptomyces avermitilis. Abamectin (avermectin B1) was introduced in 1985 as a crop insecticide against mites and some insect species. The semisynthetic derivative ivermectin (22,23-dihydroavermectin B1) was introduced commercially in 1981 as an anthelmintic. T

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